Presenting Boppli

Accurate1, non-invasive, continuous, wireless BP monitoring for neonatal and pediatric patients.

Boppli is designed to be a highly-advanced non-invasive blood pressure monitoring device that is ideal for fragile neonatal infants in the NICU. It will provide an option for moderately and mildly sick patients who require continuous blood pressure measurements, without the potential complications of an arterial line.

Boppli has the potential to revolutionize the standard of care for continuous blood pressure monitoring for neonates. Our technology is designed to be easier to use than a standard blood pressure cuff and safer than an arterial line. It’s non-invasive, painless, wireless, and silent.


2020 FDA Breakthrough Device Designation


2020 SWPDC Pediatric Device Award


2019 Winner of the NCC Pediatric Device Pitch Competition


2020 NCC-PDI MedTech Innovator Pediatric Accelerator

Our NICU Platform:


The Boppli Band Wearable Sensor


The Bedside Device


The Boppli Band Wearable Sensor

The Boppli Band is a single-use, self-powered blood pressure monitor that uses a thin, flexible sensor to continuously measure blood pressure non-invasively.

The Boppli Band is simply placed on the arm or foot of an infant to obtain a pulse waveform signal. Data is streamed continuously to a bedside device to provide detailed information including mean arterial pressure, systolic blood pressure, diastolic blood pressure and heart rate.


Advanced Sensor




Low Power






Comfortable for Long Wear


The Bedside Device

The Boppli Band wirelessly connects to the Boppli Bedside Device. The Bedside Device enables live monitoring of blood pressure and heart rate, as well as review of data previously recorded with the Boppli Band.




Blood pressure values from Machine Learning Trained Algorithms

Boppli Impact



One fewer wire.

With Boppli’s wireless design for blood pressure monitoring, neonates will have one fewer wire tying them down. This can facilitate Kangaroo care, a special skin-to-skin bonding experience which can achieve positive outcomes such as less pain, improved weight gain, and earlier discharge.2



Less trauma.

Families with children in the NICU have a higher chance of experiencing PTSD, anxiety, & depression.3, 4, 5  Boppli’s goal of enabling more timely care without pain or risk potentially results in earlier discharge.



Alleviate caseload.

Studies show missed care among NICU nurses could increase the length of stay.6, 7 PyrAmes’ continuous blood pressure monitoring has the potential to alleviate caseload and focus nursing efforts to minimize chances of missed care.



More informed, timely decisions.

PyrAmes’ innovative method of continuous monitoring blood pressure is intended to provide physicians the opportunity to observe blood pressure changes in real-time, enabling them to make better informed and timely decisions to optimize patient care and interventions.


Hospital Administration

Improved treatment, reduced costs.

Boppli’s goal of enabling non-invasive, continuous blood pressure monitoring will allow providers to offer improved patient experience and treatment with less risk of complications at a reduced cost.

From the Experts

"I have spent my career working with fragile and critically ill children, and it is clear that we need a safer alternative to monitor blood pressure than arterial catheters. The platform PyrAmes has developed has the potential to reshape medical care and provide vast benefit to patients and clinicians."

Thomas M. Krummel, MD, FACS, FAAP

Emile Holman Professor and Chair Emeritus, Department of Surgery, Stanford University School of Medicine. William E. Ladd Medal Winner

1 - Quan, X.; Liu, J.; Roxlo, T.; Siddharth, S.; Leong, W.; Muir, A.; Cheong, S.-M.; Rao, A. Advances in Non-Invasive Blood Pressure Monitoring. Sensors 2021, 21, 4273.

2 -Bonner, O., Beardsall, K., Crilly, N., & Lasenby, J. (2017). ‘There were more wires than him’: The potential for wireless patient monitoring in neonatal intensive care. BMJ Innovations, 3(1), 12. doi:10.1136/bmjinnov-2016-000145

3 -Hynan, M. T., Mounts, K. O., & Vanderbilt, D. L. (2013). Screening parents of high-risk infants for emotional distress: Rationale and recommendations. Journal of Perinatology, 33(10), 748-753. doi:10.1038/jp.2013.72

4 -Yildiz, P. D., Ayers, S., & Phillips, L. (2017;2016;). The prevalence of posttraumatic stress disorder in pregnancy and after birth: A systematic review and meta-analysis. Journal of Affective Disorders, 208, 634-645. doi:10.1016/j.jad.2016.10.009

5 -Lotterman, J. H., Lorenz, J. M., & Bonanno, G. A. (2018;2019;). You Can’t take your baby home yet: A longitudinal study of psychological symptoms in mothers of infants hospitalized in the NICU. Journal of Clinical Psychology in Medical Settings, 26(1), 116-122. doi:10.1007/s10880-018-9570-y

6 -Tubbs-Cooley, H. L., Pickler, R. H., & Meinzen-Derr, J. K. (2015;2014;). Missed oral feeding opportunities and preterm infants' time to achieve full oral feedings and neonatal intensive care unit discharge. American Journal of Perinatology,32(1), 001-008. doi:10.1055/s-0034-1372426

7 -Tubbs-Cooley, H. L., Mara, C. A., Carle, A. C., Mark, B. A., & Pickler, R. H. (2018;2019;). Association of nurse workload with missed nursing care in the neonatal intensive care unit. JAMA Pediatrics, 173(1), 44-51. doi:10.1001/jamapediatrics.2018.3619